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A new study, led by Dr. Lorenza Putignani from the Bambino Gesù Children’s Hospital in Rome (Italy), has found that gut microbiota may promote gut inflammation and activation of an immune response in PANS/PANDAS patients.

The researchers collected three fecal samples over consecutive days and, using 16S ribosomal ribonucleic acid (rRNA)-based metagenomics, they analyzed the gut microbiota composition of a cohort of 30 PANS/PANDAS patients aged 4-16 years (20 males and 10 females), comparing them with 70 healthy controls.

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